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Bone formation occurred through GLP-1 regulation of the Wnt signaling pathway, resulting in a reduction of RANKL expression and increased levels of OPG and osteocalcin

A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity

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This trial showed that patients who received semaglutide had a 26% lower risk of the primary composite outcome than the placebo group, principally driven by a significant 39% reduction in nonfatal stroke, with no significant difference in the rate of cardiovascular death